Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Herpes Simplex Virus 2

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    32 result(s) found for: Herpes Simplex Virus 2. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2006-005010-12 Sponsor Protocol Number: CFAM810B2301 Start Date*: 2007-04-02
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multicenter, open-label, single-arm study to evaluate the single-dose pharmacokinetics, acceptability and safety of famciclovir oral pediatric formulation in infants 1 month to <1 year of age wit...
    Medical condition: herpes simplex or varicella zoster virus infections in infants 1 month to <1 year of age
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019948 Herpes simplex LLT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005835-14 Sponsor Protocol Number: Acyclovir01/08 Start Date*: 2008-11-26
    Sponsor Name:MIPHARM
    Full Title: Efficacy and tolerability of a new topical formulation of Acyclovir gel (Acyclorir Liquipatch) given 3 times/day in the treatment of herpes simplex labialis. An open-label, blind controlled, random...
    Medical condition: Herpes Simplex Labialis on the perioral area
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019948 Herpes simplex LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-001572-11 Sponsor Protocol Number: LLB-2019-01 Start Date*: 2020-08-05
    Sponsor Name:LABO’LIFE Belgium sprl
    Full Title: Randomized, placebo-controlled, double-blind study to evaluate the efficacy of 2LHERP® in patients with recurrent genital herpes infections.
    Medical condition: Patients presenting recurrent genital herpes infections (4 or more episodes within the 12-months’ period prior to their study entry).
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10019972 Herpes viral infections HLT
    21.1 10021881 - Infections and infestations 10019948 Herpes simplex PT
    20.1 10021881 - Infections and infestations 10018150 Genital herpes PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-000549-38 Sponsor Protocol Number: LIP-01-01 Start Date*: 2018-01-29
    Sponsor Name:Laboratorios Ojer Pharma S.L.
    Full Title: An open-label study to investigate the local tolerability and acceptability of Lipovir® Gel (Acyclovir 5%) compared to Zovirax® Cream (Acyclovir 5%) on patients with Recurrent Herpes Labialis
    Medical condition: Herpes labialis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10019948 Herpes simplex PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003586-35 Sponsor Protocol Number: 215336 Start Date*: 2022-01-25
    Sponsor Name:GlaxoSmithKline Biologicals SA
    Full Title: A Phase I/II, observer-blind, randomised, placebo controlled, multi-country study to evaluate reactogenicity, safety, immune response, and efficacy of an HSV-targeted immunotherapy in healthy parti...
    Medical condition: Recurrent genital herpes
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10018150 Genital herpes PT
    21.1 10021881 - Infections and infestations 10073931 Genital herpes simplex PT
    24.0 10021881 - Infections and infestations 10084891 Anal herpes LLT
    20.1 10021881 - Infections and infestations 10054225 Anogenital herpes LLT
    20.1 10021881 - Infections and infestations 10018151 Genital herpes, unspecified LLT
    20.0 10021881 - Infections and infestations 10019937 Herpes genital LLT
    20.0 10021881 - Infections and infestations 10019938 Herpes genitalis LLT
    20.0 10021881 - Infections and infestations 10019997 Herpetic infection of penis LLT
    20.1 10021881 - Infections and infestations 10020003 Herpetic ulceration of vulva LLT
    20.1 10021881 - Infections and infestations 10020004 Herpetic vulvovaginitis LLT
    21.1 10021881 - Infections and infestations 10065050 Perianal herpes simplex LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing) DE (Trial now transitioned) ES (Ongoing) EE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004835-19 Sponsor Protocol Number: 38RC16.015 Start Date*: 2017-07-20
    Sponsor Name:University Hospital Grenoble
    Full Title: Dexamethasone in Herpes Simplex Virus Encephalitis Open label Randomized Controlled Trial with an Observer-blinded evaluation at 6 months
    Medical condition: HSV encephalitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000013665 10014590 Encephalitis herpes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000880-26 Sponsor Protocol Number: HTX101-02G Start Date*: 2019-09-03
    Sponsor Name:Heidelberg ImmunoTherapeutics GmbH
    Full Title: A Randomized, Double-Blind, Double-Dummy Phase II Study of Single Dose HDIT101 versus Standard of Care Valaciclovir in Patients with Chronic Recurrent Anogenital HSV-2 Infection
    Medical condition: Chronic recurrent anogenital HSV-2 infection
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10019938 Herpes genitalis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000926-24 Sponsor Protocol Number: HTX101-03L Start Date*: 2020-08-17
    Sponsor Name:Heidelberg ImmunoTherapeutics
    Full Title: A Randomised, Double-Blind Phase II Trial of Topical HDIT101 versus Placebo in Patients with Chronic Recurrent HSV-1 Infection and Orolabial Lesion
    Medical condition: Chronic Herpes Simplex Virus-1 Infection
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10073933 Herpes simplex oral LLT
    22.0 100000004862 10082141 Herpes simplex labialis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004316-31 Sponsor Protocol Number: FPP4-DE-401 Start Date*: 2009-02-23
    Sponsor Name:Novartis Consumer Health S.A.
    Full Title: A randomised, double-blind, vehicle controlled, single centre, parallel group, comparative study of the efficacy of penciclovir 10 mg/g (1%) cream in preventing the appearance of classical lesions ...
    Medical condition: Cold Sores caused by the herpes simplex virus (HSV) type 1.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049352 Cold sores lip LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001451-30 Sponsor Protocol Number: UMCN-AKF12.07 Start Date*: 2019-06-17
    Sponsor Name:Radboud university medical center
    Full Title: Pharmacokinetics of a new paediatric formulation of valacyclovir used for prophylaxis and treatment of VZV and HSV infections in children, phase II (VALID II)
    Medical condition: Herpes virus infections, especially Herpes Simplex and Varicella Zoster.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10019973 Herpes virus infection PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023156-89 Sponsor Protocol Number: V212-011 Start Date*: 2011-02-24
    Sponsor Name:Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc
    Full Title: Ensayo clínico en fase III, aleatorizado y controlado con placebo para estudiar la seguridad y la eficacia de V212 en pacientes adultos con tumor sólido o neoplasia hematológica. A Phase III Rando...
    Medical condition: Incidence of Herpes Zoster in adults with solid tumor or hematologic malignancy Incidencia de Herpes Zoster en pacientes adultos con tumor sólido o neoplasia hematológica.
    Disease: Version SOC Term Classification Code Term Level
    13 10019974 Herpes zoster LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) CZ (Completed) GB (Completed) SK (Completed) AT (Completed) BE (Completed) EE (Completed) LT (Completed) GR (Completed) BG (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004441-17 Sponsor Protocol Number: CFAM810B2303 Start Date*: 2016-04-12
    Sponsor Name:Novartis Pharmaceuticals
    Full Title: A Multicenter, Open-label, Single-arm, Two-step Study to Evaluate the Safety and Single-dose Pharmacokinetics of Famciclovir and Multiple-dose Safety After Administration of Famciclovir Oral Pediat...
    Medical condition: Herpes Simplex
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-006940-69 Sponsor Protocol Number: 601 Start Date*: 2010-05-20
    Sponsor Name:Lund University Hospital
    Full Title: Add-on treatment of mental illness with anti-viral medicine
    Medical condition: Schizophrenia, bipolar disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000577-22 Sponsor Protocol Number: AKF-UMCN11.05 Start Date*: 2012-07-17
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Palatability testing of a new paediatric formulation of valacyclovir for the prophylaxis and treatment of VZV and HSV infections in children – VALID 0
    Medical condition: Herpes virus infections, especially Herpes Simplex, Varicella Zoster and Cytomegalovirus
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10019973 Herpes virus infection PT
    Population Age: Children, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-004869-88 Sponsor Protocol Number: HS2116100 Start Date*: 2016-12-21
    Sponsor Name:GlaxoSmithKline K.K. (GSK)
    Full Title: A multicenter, open-label study to evaluate preventive efficacy for herpes simplex virus infection and safety of 256U87 (valaciclovir hydrochloride) in adult and pediatric hematopoietic stem cell t...
    Medical condition: Herpes simplex virus (HSV) infection before and after hematopoietic stem cell transplantation.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2019-001085-15 Sponsor Protocol Number: LLB-2018-01 Start Date*: 2019-11-06
    Sponsor Name:LABO’LIFE Belgium sprl
    Full Title: Randomized, placebo-controlled, double-blind study to evaluate the efficacy of 2LHERP® in patients with recurrent orofacial herpes infections.
    Medical condition: Patients presenting recurrent orofacial herpes infections (6 or more episodes within the 12-months’ period prior to their study entry).
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10019972 Herpes viral infections HLT
    20.1 10021881 - Infections and infestations 10067152 Oral herpes PT
    21.1 10021881 - Infections and infestations 10019948 Herpes simplex PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000033-41 Sponsor Protocol Number: AMEN1 Start Date*: 2020-02-17
    Sponsor Name:Aalborg University Hospital
    Full Title: Aciclovir for HSV-2 meningitis: A double-blind randomised controlled trial (AMEN)
    Medical condition: Viral meningitis caused by Herpes simplex virus 2
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10047469 Viral meningitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000612-24 Sponsor Protocol Number: WN06AN002 Start Date*: 2006-03-28
    Sponsor Name:Greater Glasgow Health Board (North Glasgow University Hospitals Division)
    Full Title: Trial of Aciclovir Prophylaxis of Herpes Infections in Critical Care
    Medical condition: Herpes simplex virus infection - prophylaxis in critically ill patients on ventilators
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-003953-34 Sponsor Protocol Number: 101-001 Start Date*: 2009-12-14
    Sponsor Name:D2 Derma Europe Ltd.
    Full Title: A randomized, placebo-controlled, active comparator, observer-blinded multicentre phase II trial to evaluate the efficacy and safety of D2D001 in the treatment of HSV type 1 infection in the region...
    Medical condition: Herpes simplex virus type 1 infection in the region of the mouth and the openings of the nose
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004940-27 Sponsor Protocol Number: AIC316-03-II-01(Phase3) Start Date*: Information not available in EudraCT
    Sponsor Name:AiCuris Anti-infective Cures GmbH
    Full Title: A randomized, open-label, multi-center, comparative trial, to assess the efficacy and safety of pritelivir versus foscarnet for the treatment of acyclovir-resistant mucocutaneous HSV infections in ...
    Medical condition: Acyclovir-resistant mucocutaneous HSV infections in immunocompromised subjects
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing) DE (Ongoing) BE (Ongoing) IT (Ongoing) GR (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Mon May 20 00:20:47 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA